OBJECTIVES -Define the main type of gene regulators

• Exemplify of gene regulation
• Apply a experimental design using gene regulation

Topics:

• Operons, repressors, activators, & paradigms of gene regulation
• Global regulons: regulons and stimulons
• Global regulatory mechanisms
• Regulatory cascades, two component sensors, sensor-kinases & response regulators, enhancers & silencers
• Regulatory RNAs
• Global gene expression studies, genetic reporters.

REFRENCES

Global regulation - regulons and stimulons.pdf

Regulation of gebe expression - Operons.pdf

Sigma factors - key molecules in mycobacterium tuberculosis phisiology and virulence.pdf

Noncoding RNA in Mycobacteria.pdf

Two component regulatory systems in mycobacteria.pdf

Regulated expression systems for Mycobacteria and their applications.pdf

Construction of Conditional Knockdown mitants in Mycobacteria.pdf